Targeting RAS phosphorylation in cancer therapy: Mechanisms and modulators - ScienceDirect
The Importance of Mg2+‐Free State in Nucleotide Exchange of Oncogenic K‐Ras Mutants - Pálfy - Chemistry – A European Journal - Wiley Online Library
Simulating Ras: 30 years of progress - NCI
The Activation of RalGDS Can Be Achieved Independently of Its Ras Binding Domain: IMPLICATIONS OF AN ACTIVATION MECHANISM IN Ras EFFECTOR SPECIFICITY AND SIGNAL DISTRIBUTION - ScienceDirect
Pharmaceuticals | Free Full-Text | A Rational Design of α-Helix-Shaped Peptides Employing the Hydrogen-Bond Surrogate Approach: A Modulation Strategy for Ras-RasGRF1 Interaction in Neuropsychiatric Disorders
Potential for Next Generation RAS Inhibitors in Adult and Pediatric Cancers
Integrated RAS signaling defined by parallel NMR detection of effectors and regulators | Nature Chemical Biology
Structural Insights into the BRAF Monomer-to-dimer Transition Mediated by RAS Binding | bioRxiv
The Ras switch in structural and historical perspective
Phosphorylation promotes binding affinity of Rap-Raf complex by allosteric modulation of switch loop dynamics | Scientific Reports
Biomolecules | Free Full-Text | Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID-19—The Role of RAGE-RAS Crosstalk
RAS(ON) Inhibitors | Revolution Medicines
The current state of the art and future trends in RAS-targeted cancer therapies | Nature Reviews Clinical Oncology
JPM | Free Full-Text | Targeting KRAS in Pancreatic Cancer
Pharmaceuticals | Free Full-Text | A Rational Design of α-Helix-Shaped Peptides Employing the Hydrogen-Bond Surrogate Approach: A Modulation Strategy for Ras-RasGRF1 Interaction in Neuropsychiatric Disorders
Simulating Ras: 30 years of progress - NCI
The Ras switch in structural and historical perspective
Cancers | Free Full-Text | Cutting the Brakes on Ras—Cytoplasmic GAPs as Targets of Inactivation in Cancer
Mapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution | eLife
Modeling the Role of G12V and G13V Ras Mutations in the Ras-GAP-Catalyzed Hydrolysis Reaction of Guanosine Triphosphate | Biochemistry
Simulating Ras: 30 years of progress - NCI
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling | Journal of Medicinal Chemistry
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions | eLife
